What are polynucleotides?

Polynucleotides, also known as PDRN therapy, are derived from salmon DNA. This treatment stimulates the regeneration of skin cells and activates fibroblasts to produce more collagen and elastin. In the context of aesthetic medicine, they are used as biostimulators to improve skin quality, enhance elasticity, reduce fine lines, support tissue repair, and promote overall skin rejuvenation. biostimulator injectables: they do not work by adding volume (like fillers), but by strengthening and improving the skin from within.

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How do polynucleotides work?

At Nurses Inc., we work with products from Croma-PhilArt, these contain highly purified polynucleotides (PN-HPT technology), which are injected into the dermis to support the skin.

Main effects:
Hydration — they attract and retain water in the skin, resulting in an immediate improvement in hydration balance and suppleness.
Stimulation of fibroblasts — these cells produce collagen and elastin, contributing to firmer and more resilient skin.
Antioxidant effects — they help neutralize free radicals, which slows down skin aging.
Improved skin texture — overall skin quality, elasticity, and structure may improve.

Polynucleotides stimulate the skin itself to regenerate instead of artificially adding volume — which makes them ideal for those seeking natural improvement without altering facial volume.

Polynucleotides

Course of 3 Polynucleotide Treatments
600
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What does a treatment involve in practice?

A treatment with polynucleotides focuses on:

Skin quality

• Finer texture
• Improved hydration
• Improved elasticity and resilience
• Reduced dull or tired appearance

Under-eye area

Specific formulations can revitalize the delicate skin around the eyes, reduce fine lines, and improve elasticity.

Treatment: 20 min.

Type of injectable: Skin improvement

Result: After 3 weeks

Repeat advice: Treatment course: 2–4 sessions, spaced 3–4 weeks apart.

Effect 6 - 12 month average

What results and treatment course can you expect?

When will I see results?
You often see improvement in hydration and skin quality within 1 to 2 weeks, with further optimization over several weeks after multiple sessions.

How long do the results last?
Results can last for several months — approximately 6–12 months — depending on skin condition and lifestyle.

Number of treatments
A course of 2–4 sessions is often recommended, spaced approximately 2–3 weeks apart for optimal results.

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Safety and side effects

Polynucleotides are biocompatible and are generally well tolerated. As with any injectable treatment, temporary redness, swelling, or mild tenderness may occur around the injection sites.

Price and treatment areas

The price for a treatment with polynucleotides cost €225 per treatment area.

A zone is a clearly defined treatment area, such as:
• the area around the eyes
• the upper face
• the lower face

During the consultation, we discuss which treatment area(s) best suit your skin condition and goals. This way, you know exactly what to expect in advance, and together we choose an appropriate treatment plan. a natural improvement in skin quality..

Polynucleotides

Course of 3 Polynucleotide Treatments
600

Polynucleotides – Skin improvement from within

Polynucleotides support the skin in repair, hydration, and renewal. Without adding volume, but with visible improvement in skin quality, elasticity, and overall radiance. An ideal treatment for those who choose natural skin enhancement.